Technology News, IT News, and Press release service Submit Press Release

Information Tech News & Press Release Distribution

Press release distribution service

Home | Search Global IT News:
IT News & Press Release Distribution:

Immune Checkpoint Inhibitors Market Size, Share and Forecast 2019-2026

 



(IT-NEWSWIRE.COM, December 17, 2019 ) Market Overview
The immune checkpoint inhibitor is a drug made of antibodies that unleashes an immune system attack on cancer cells.

Checkpoint inhibitors seek to overcome one of cancer’s primary defenses against an immune system attack.

Immune system T cells patrol the body constantly for signs of disease or infection.
When they encounter another cell, they probe specific proteins on its surface, which serve as a symbol of the cell’s identity.

Checkpoint inhibitors block normal proteins on cancer cells or the proteins on T cells. The result is to remove the blinders that prevented T cells from recognizing the cells as cancerous and leading an immune system assault on them.

Three checkpoint inhibitors have received rapid approval from the U.S. Food and Drug Administration for cancer, including ipilimumab, pembrolizumab, and nivolumab.

The global immune checkpoint inhibitors market was worth XX billion in 2018 and is forecasted to reach XX billion by 2026, at a CAGR of XX% during the forecast period.

Download free report sample @ https://www.datamintelligence.com/download-sample/immune-checkpoint-inhibitors-market


Market Dynamics
The rising prevalence of cancer is one of the factors fueling the global immune checkpoint inhibitors market.

According to the National Cancer Institute, in 2018, an estimated 1,735,350 new cases of cancer in the United States and 609,640 people will die from the disease.

The most common cancers are breast cancer, lung and bronchus cancer, prostate cancer, colon and rectum cancer, melanoma of the skin, bladder cancer, non-Hodgkin lymphoma, kidney and renal pelvis cancer, endometrial cancer, leukemia, pancreatic cancer, thyroid cancer, and liver cancer.

The number of new cases of cancer is 439.2 per 100,000 men and women per year. The number of cancer deaths is 163.5 per 100,000 men and women per year in the U.S.

According to Cancer Research U.K., There are more than 360,000 new cancer cases in the UK every year, that’s nearly 990 every day. The incidence rates for all cancers combined are projected to rise by 2% in the UK between 2014 and 2035, to 742 cases per 100,000 people by 2035.

In U.K, there were around 183,000 new cancer cases in male and approximately 177,000 new cancer cases in the female, in 2015.

Market – Segment Analysis
Based on drug class the global market for immune checkpoint inhibitors is broadly segmented as by PD- 1 inhibitors, PD- L1 inhibitors, and CTLA- 4.
Currently, PD- 1 inhibitors are the dominant segment, and it accounts for approximately XX% of the market, due to the regulatory approval for PD- 1 inhibitors and strategic alliance between companies for clinical collaboration.

For instance, in December 2018, Bristol-Myers Squibb Company and Vedanta Biosciences have signed an agreement for clinical trial collaboration to evaluate Bristol-Myers Squibb’s programmed death-1 (PD-1) immune checkpoint inhibitor Opdivo in combination with Vedanta Biosciences’ VE800, a rationally-defined human bacterial consortium, in patients with advanced or metastatic cancers.

In October 2018, Sanofi and Regeneron’s received FDA approval for cemiplimab (REGN-2810), a programmed cell death protein 1 (PD-1) checkpoint inhibitor.

In January 2018, Bristol-Myers Squibb Company and Ono Pharmaceutical Company, Ltd. signed a global patent license agreement with Merck & Co., Inc. to settle all patent-infringement litigation related to Merck’s PD-1 antibody Keytruda (pembrolizumab).

In July 2015, Bristol-Myers Squibb Company received European Commission approval for Nivolumab BMS. Nivolumab BMS is for the treatment of locally advanced or metastatic squamous (SQ) non-small cell lung cancer (NSCLC) after prior chemotherapy. Nivolumab is also the first and only PD-1 immune checkpoint inhibitor to demonstrate overall survival (OS) in previously-treated metastatic SQ NSCLC.

Geographical Analysis
The global immune checkpoint inhibitors market is segmented into North America, Europe, Asia Pacific, South America, and ROW.

North America is dominating the global immune checkpoint inhibitors market, due to increasing regulatory approval for immune checkpoint inhibitors, which is fueling the market growth.

For instance, in November 2018, the Food and Drug Administration (FDA) has approved the checkpoint inhibitor Keytruda (pembrolizumab) for people with hepatocellular carcinoma (HCC), the most common type of cancer that originates in the liver.

In September 2018, the U.S. Food and Drug Administration has approved Libtayo (cemiplimab-rwlc) injection for intravenous use for the treatment of patients with metastatic cutaneous squamous cell carcinoma (CSCC) or locally advanced CSCC. Libtayo works by targeting the cellular pathway known as PD-1 (a protein found on the body’s immune cells and some cancer cells).

In May 2017, AstraZeneca received the US Food and Drug Administration (FDA) approval for Imfinzi (duralumin) PD-L1. Infiniti is indicated for the treatment of patients with locally advanced or metastatic urothelial carcinoma (UC).

Competitive Trends
The strategic alliance between companies for immune checkpoint inhibitors is one of the critical factor driving the global immune checkpoint inhibitors market.
For instance, in October 2018, Bristol-Myers Squibb Company and Compugen, have entered into a clinical trial collaboration to evaluate the safety and tolerability of COM701, an investigational anti-PVRIG antibody, in combination with programmed death-1 (PD-1) immune checkpoint inhibitor Opdivo (nivolumab), in patients with advanced solid tumors.

In August 2018, Ono Pharmaceutical Co. Ltd., have entered into the clinical collaboration agreement with Bristol-Myers Squibb Company and Clovis Oncology Inc. to evaluate the combination therapy of ONO/BMS’s Opdivo, a human anti-human PD-1 monoclonal antibody, and Clovis’ Rubraca8, an inhibitor of poly polymerase (PARP) in multiple tumor types including ovarian cancer, breast cancer and prostate cancer in Japan, South Korea and Taiwan.

In April 2015, MedImmune, and Juno Therapeutics, Inc., have entered into a new collaboration to conduct combination clinical trials in immuno-oncology with one of Juno’s investigational CD19-directed chimeric antigen receptor (CAR) T cell candidates and MedImmune’s investigational programmed cell death ligand 1 (PD-L1) immune checkpoint inhibitor, MEDI4736.

View full report sample @ https://www.datamintelligence.com/research-report/immune-checkpoint-inhibitors-market

For any enquiry about the report@ https://www.datamintelligence.com/enquiry/immune-checkpoint-inhibitors-market

About Us:
DataM Intelligence was established on an elemental idea of publishing Advanced Market Research Reports with precise data points & utmost accuracy that will accelerate the decision-making in designing disruptive solutions. We monitor and analyze the market by dissecting various parameters such as market influencers, competitive intensity, innovations, trends, and emerging products.

For more information:
Sai Kiran
Sales Manager
Website: www.datamintelligence.com
Email: info@datamintelligence.com



DataM Intelligence

Sai Kiran

+1 877 441 4866

pr@datamintelligence.com

Source: EmailWire.Com

Source: EmailWire.com

Information Technology Resources
  • Application Software
  • Bioinformatics
  • Computers
  • Computer Games
  • Enterprise Software
  • Graphics/Printing/CAD
  • Hardware/Peripheral
  • industrial Computers
  • Information
  • Internet
  • Multimedia
  • Networking
  • Public Sector
  • Robotics
  • Semiconductor
  • Software
  • Telecommunications
  • Webmaster
  • Information Technology (IT) Advertisement
    Information Technology Sponsors



    Information Technology Publications
    We are pleased to offer you this exciting, new, and entirely free professional resource. Visit our Free Information Technology resource center today to browse our selection of 600+ complimentary Information Technology magazines, white papers, webinars, podcasts, and more. Get popular titles including:

    The Integration Journey—a Field Guide to Enterprise Integration for SOA
    Government Technology\'s Public CIO
    Protecting Content During Business Disruption: Are You Covered?

    No credit cards, coupons, or promo codes required. Try it today!

    Press release distribution service

    ITPresswire.com is part of GropWeb Network, online properties of GroupWeb Media LLC. Copyright © GroupWeb Media LLC. All Rights Reserved.

    :: Home: :: Submit Press Release :: Subscribe to News :: Shop Online :: Contact Us :: Help

    For unlimited press release distribution for $99 per month, call (281) 645-4086 or start posting your press releases online at EmailWire.com.
    Copyright 2008 GroupWeb Media LLC
    GroupWeb Media Network

    Aviation-NewsWire | ArtNewsWire | Auction NewsWire | CRM NewsWire | ePhotoNewsWire | Energy Industry | EstateNewsWire | Entertainment-NewsWire.com | Food Beverage News | Glamour NewsWire | Health NewsWire | Hosting NewsWire | i-Auto NewsWire | i-Business News | i-Homeland Security.Com | iMac-NewsWire.Com | i-Press-Release-Service | i-SoftwareNews.com | iT-NewsWire.Com
    | i-TravelNewsWire.Com | MoneyNewsWire.Net | Movie-Stars-News.Com | MSNewsWire.Net | PharmaNewsWire.Com | Publishing-NewsWire.Com | RSSNewsWire.Net | Telecom-NewsWire.Net | Transportation-News.Com | USGovernment-News.Com | WebPosters.Net | Wireless-NewsWire.Com | VoIPNewsWire.Net | XSportsWorld.Net
    ITPresswire.com - Newswire and Press Release service of GroupWeb Media LLC